Background: Chronic kidney disease patients are at a greater risk for\nnephropathy requiring dialysis after percutaneous coronary intervention.\nSuch patients are usually deferred due to fear of â??Renalismâ?. Objectives\nThis study assesses the outcome of Low dose contrast protocol during PCI\nin CKD patients whose e-GFR < 60 ml/min/1.72 m and investigates a safety\nmargin for contrast use in these high-risk categories. (A) Methods: Patients\nwere into three groups according to CV/e-GFR ratio: Group low-dose:\nCV/e-GFR ratio < 2.0 Group (B) medium-dose: CV/e-GFR ratio > 2.0 and <\nMACD (5Ã? bodyweight\\s.creatinine). Group (C) high-dose: CV/e-GFR ratio\n> MACD. Results: A total of 73 patients were enrolled. Average age was\n54 } 8 years, 81.4% were male and 18.6% were females and 52% were diabetic.\nMean baseline e-GFR was 40 } 8.0 ml/min/1.73 m2. Contrast Volume\nused in group A was (58.26} 15.05) (n = 24), in group B (109.42 }\n17.11) (n = 26) and in group C (304.5 } 60.30) (n = 23), respectively. The\nincidences of CI-AKI in the 3 groups were 0%, 11.5% and 35%, respectively\n(p = 0.02). All-cause death 0%, 17% and introduction of maintenance hemo\ndialysis was 0%, 11.5% and 26%, respectively (p < 0.01). Conclusion: Low\ndose contrast protocol is safe, effective and easily applicable technique\nwithout CI-AKI or death. CV/e-GFR < 2 is a safe ratio and can be achieved\nwithout IVUS use with good outcomes.
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